Study questions:
- What are the 4 phases of wound healing?
- What the 3 primary cells are important during wound healing?
- What signaling molecules are involved in wound healing?
- Define autocrine, paracrine, juxtacrine and encocrine.
- List the various extracellular components involved in wound healing.
- What are 5 functions of the ECM?
- What happened in the inflammatory phase?
- What interleukin is released when wounding occurs?
- What is released from the platelets during degranulation?
- How does the platelet shape change during activation?
- Which healing phase is most vulnerable to develop infection?
- What two cells are very important during the inflammatory phase?
- What happens during the early inflammatory phase of wound healing?
- What happens during the late inflammatory phase of wound healing?
- What is the function of the metalloproteases? What cell releases this enzyme?
- What events happen during the proliferative phase?
- What cells are the players during the proliferative phase?
- Describe the process of collagen synthesis in the fibroblasts.
- What is graduation tissue?
- Why does granulation tissue get pale as it matures?
- Describe what happens during epithelialization.
- What is contact inhibition?
- What happens during the maturation phase? How long does this phase last?
- What is the strength of the wound after final healing?
- What is contracture?